Reference of 111248-89-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.111248-89-6, Name is 1,3-Dihydrobenzo[c]isothiazole 2,2-dioxide, molecular formula is C7H7NO2S. In a Patent£¬once mentioned of 111248-89-6
2,1-benzisothiazoline 2,2-dioxides
This invention provides a progesterone receptor antagonist of formula 1 having the structure STR1wherein R 1, and R 2 are each, independently, hydrogen, alkyl, substituted alkyl, hydroxy, alkoxy, substituted alkoxy, aryl, substituted aryl, heteroaryl, substituted heteroaryl, arylalkyl, heteroarylalkyl, and alkynyl. R 1 and R 2 may be taken together to form a ring and together contain –CH 2 (CH 2) n CH 2 –, –CH 2 CH 2 CMe 2 CH 2 CH 2 –, –O(CH 2) P CH 2 –, O(CH 2) q O–, –CH 2 CH 2 OCH 2 CH 2 –, –CH 2 CH 2 NR 7 CH 2 CH 2 –. R 1 and R 2 may be taken together to form a double bond, the double bond having two methyl groups bonded to the terminal end, having a cycloalkyl group bonded to the terminal end, having an oxygen bonded to the terminal end, or having a cycloether bonded to the terminal end; or a double bond. R 3 is hydrogen, hydroxyl, NH 2, alkyl, substituted alkyl, alkenyl, alkynyl, substituted or, COR A. R 4 is hydrogen, halogen, –CN, –NH 2, alkyl, substituted alkyl, alkoxy, alkoxy, aminoalkyl, or substituted aminoalkyl; R 5 is a trisubstituted phenyl ring having the structure, STR2or is a five or six membered heteroaryl ring, containing 1, 2, or 3 heteroatoms selected from the group consisting of O, S, SO, SO 2 and NR 6, or pharmaceutically acceptable salt thereof.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 111248-89-6, and how the biochemistry of the body works.Reference of 111248-89-6
Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com