27148-03-4, Name is Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide, belongs to isothiazole compound, is a common compound. 27148-03-4In an article, authors is Al-Jibori, Subhi A., once mentioned the new application about 27148-03-4.
Combining anti-cancer drugs with artificial sweeteners: Synthesis and anti-cancer activity of saccharinate (sac) and thiosaccharinate (tsac) complexes cis-[Pt(sac)2(NH3)2] and cis-[Pt(tsac)2(NH3)2]
The new platinum(II) complexes cis-[Pt(sac)2(NH3)2] (sac = saccharinate) and cis-[Pt(tsac)2(NH3)2] (tsac = thiosaccharinate) have been prepared, the X-ray crystal structure of cis-[Pt(sac)2(NH3)2].H2O reveals that both saccharinate anions are N-bound in a cis-arrangement being inequivalent in both the solid-state and in solution at room temperature. Preliminary anti-cancer activity has been assessed against A549 human alveolar type-II like cell lines with the thiosaccharinate complex showing good activity.
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Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com