Name is 3-Chlorobenzo[d]isothiazole, as a common heterocyclic compound, it belongs to isothiazole compound, and cas is 7716-66-7, its synthesis route is as follows.
2)Preparation of 4-(1,2-benzisothiazol-3-yl)-1-piperazine3-chloro-(1,2-benzisothiazole) (14g, 200 mmol) and anhydrous piperazine (6.8g, 40 mmol) are placed in an egg type flask and heated at 125¡ãC for 24 hours.After completion of reaction, 52 ml of an ice-water mixture is added for quenching the reaction.The mixture is further added with 3.2g of 50percent NaOH solution, stirred 5 minutes and extracted with CH2Cl2 (50ml*3).The organic layer is washed with an ice-water mixture (50ml*2) and saturated saline (50ml*2), and dried over anhydrous MgSO4 to obtain 4-(1,2-benzisothiazol-3-yl)-1-piperazine.
7716-66-7, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,7716-66-7 ,3-Chlorobenzo[d]isothiazole, other downstream synthetic routes, hurry up and to see
Reference£º
Patent; Jiangsu Guohua Investment Co., Ltd; Shanghai Institute of Pharmaceutical Industry; EP2322520; (2011); A1;,
Isothiazole – Wikipedia
Isothiazole – ScienceDirect.com