Name is 3-Chlorobenzo[d]isothiazole, as a common heterocyclic compound, it belongs to isothiazole compound, and cas is 7716-66-7, its synthesis route is as follows.,7716-66-7
3-Chlorobenzo[d]isothia-zole (300 mg, 3.0 mmol) was dissolved in propane- 1,3 -diamine (3 mL) and heated at 8O0C for 3 h. The reaction mixture was cooled to room temperature, poured into water and extracted with ethyl acetate. The organic extract was dried over anhydrous sodium sulfate, filtered and the filtrate concentrated under reduced pressure to yield ^-(benzotdJisothiazol-S-ytypropane- 1,3-diamine as a yellow solid, (530 mg). 1H NMR (300 MHz, CDCl3): 7.8 (m, IH), 7.7 (m, IH), 7.5 (m, 2H), 7.3 (m, IH), 3.7 (m, 2H), 2.9 (t, 2H), 1.9 ppm (m, 2H).
With the complex challenges of chemical substances, we look forward to future research findings about 3-Chlorobenzo[d]isothiazole
Reference£º
Patent; RIGEL PHARMACEUTICALS, INC.; WO2006/91858; (2006); A1;,
Isothiazole – Wikipedia
Isothiazole – ScienceDirect.com