Downstream synthetic route of Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide

With the synthetic route has been constantly updated, we look forward to future research findings about Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide,belong isothiazole compound

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO446,mainly used in chemical industry, its synthesis route is as follows.,27148-03-4

General procedure: The [Zn(tsac)2(o-phen)] complex was prepared by addition of a dissolution of Zn(NO3)26H2O (14.85 mg, 0.049 mmol, 2 ml) into a thiosaccharine solution (20 mg, 0.1 mmol/ethanol:water 1:1,2 ml). A o-phenantroline solution was finally added drop by drop (ethanol:water 1:1, 2 ml) and a yellow power was obtained. The resulting yellow solid was filtered and washed with cold water. Crystals suitable for X-ray diffraction studies were produced by slow diffusion of diethyl ether to the mother solution. Yield: 74%

With the synthetic route has been constantly updated, we look forward to future research findings about Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide,belong isothiazole compound

Reference£º
Article; Delgado, Fermin; Freire, Eleonora; Baggio, Ricardo; Gonzalez Pardo, Veronica; Dorn, Viviana; Dennehy, Mariana; Inorganica Chimica Acta; vol. 479; (2018); p. 266 – 274;,
Isothiazole – Wikipedia
Isothiazole – ScienceDirect.com