2,3-Dihydrobenzo[d]isothiazole 1,1-dioxide, cas is 936-16-3, it is a common heterocyclic compound, the isothiazole compound, its synthesis route is as follows.,936-16-3
2,3-dihydro-1,1-dioxo-1,2-benzoisothiazole (150 mg, 0.887 mmol), N-Boc-bromoethylamine (238mg, 1.064mmol) And cesium carbonate (867mg, 2.66mmol) in 5ml DMF, It was then stirred overnight. On the following day, after the reaction was detected by TLC, water was added for extraction. It was washed with saturated brine and dried over anhydrous sodium sulfate. Suction filtration, the filtrate was concentrated under reduced pressure, the crude product was separated by column chromatography, 124 mg of a white solid were obtained with a yield of 45%.
936-16-3 is used more and more widely, we look forward to future research findings about 2,3-Dihydrobenzo[d]isothiazole 1,1-dioxide
Reference£º
Patent; Chinese Academy Of Sciences Shanghai Pharmaceutical Institute; Zhang Ao; Meng Linghua; Ding Jian; Chen Shulun; Ding Chunyong; Guo Wei; (26 pag.)CN110143955; (2019); A;,
Isothiazole – Wikipedia
Isothiazole – ScienceDirect.com