Extracurricular laboratory: Synthetic route of 87691-88-1

As the rapid development of chemical substances, we look forward to future research findings about 87691-88-1

3-Piperazinobenzisothiazole hydrochloride, cas is 87691-88-1, it is a common heterocyclic compound, the isothiazole compound, its synthesis route is as follows.,87691-88-1

The above intermediate IV (0.01 mol) and the hydrochloride salt of the piperazine compound (V) (0.01 mol)Dissolved in DMF (100 mL) and added K2CO3 (0.02 mol).According to the general operation three,Preparation of 3-(4-(4-(5-fluoro-1H-indol-3-yl)butyl)piperazin-1-yl)benzo[d]isothiazole (VI-3) hydrochloride ( White solid) 3.11 g, yield 70%.

As the rapid development of chemical substances, we look forward to future research findings about 87691-88-1

Reference£º
Patent; Shanghai Pharmaceutical Industry Institute; China Pharmaceutical Industry Zongyuan; Li Jianqi; Gu Zhengsong; Zhou Ainan; Xiao Ying; (26 pag.)CN109467554; (2019); A;,
Isothiazole – Wikipedia
Isothiazole – ScienceDirect.com