18480-53-0, 3,4-Dichloroisothiazole-5-carboxylic acid is a isothiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
2.1. Synthesis of ethyl 3,4-dichloroisothiazole-5-carboxylate: 15 g of 3,4-dichloroisothiazole-5-carboxylic acid (75.7 mmol) were dissolved in 300 ml of ethanol and 8.4 ml of concentrated sulphuric acid were added. The mixture was stirred under reflux for 20 h. The reaction mixture was then concentrated to half the original volume, neutralized with saturated NaHC03, added to water and extracted with dichloromethane. The dichloromethane phases were dried and carefully concentrated on a rotary evaporator. Yield: 15.2 g (89percent of theory).’H-NMR (400 MHz, CDC13delta, ppm) 4.44 (q,2H), 1.42 (tr,3H).
As the paragraph descriping shows that 18480-53-0 is playing an increasingly important role.
Reference£º
Patent; BAYER CROPSCIENCE AKTIENGESELLSCHAFT; TIEBES, Joerg; MOSRIN, Marc; REY, Jullien; DOeLLER, Uwe; DROeGE, Thomas; MAECHLING, Simon; SCHMIDT, Jan Peter; TELSER, Joachim; SCHMUTZLER, Dirk; DIETRICH, Hansjoerg; GATZWEILER, Elmar; ROSINGER, Christopher Hugh; BERNIER, David; CRISTAU, Pierre; TSUCHIYA, Tomoki; (180 pag.)WO2016/102420; (2016); A2;,
Isothiazole – Wikipedia
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